ΕΜΒΟΛΙΟ ΚΑΤΑ ΤΟΥ ΚΑΡΚΙΝΟΥ ! ! !

Patent application title: 

CANCER VACCINE COMPRISING A MUCIN 1 (MUC1) T CELL EPITOPE-DERIVED PEPTIDE

Inventors:  Geoffrey Allan Pietersz  Vasso Apostolopoulos  Ian Farquhar Campbell McKenzie
Agents:  SHERIDAN ROSS PC
Assignees:  4G VACCINES PTY LTD
Origin: DENVER, CO US
IPC8 Class: AA61K3900FI
USPC Class: 4241851
Patent application number: 20090317414

Abstract:
A cancer vaccine, and a composition for the ex vivo priming of dendritic cells, is disclosed which comprises a MUC1 T cell epitope-derived peptide or peptide analogue capable of provoking a cytotoxic T cell immune response. Particular MUC1 T cell epitope-derived peptides disclosed include TTAPPVHGL, STAPPVHGL, STAPPAHGL, TTAPPAHGV and SAPDTYPAL.

FIELD OF THE INVENTION

[0001]The present invention relates to the prevention and/or treatment of cancer characterised by Mucin 1-positive (MUC1⁺) tumour cells. More particularly, the present invention relates to a cancer vaccine and composition for the ex vivo priming of dendritic cells, each comprising a MUC1 T cell epitope-derived peptide or peptide analogue.


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